Appendicitis: Antibiotics vs. Surgery in Pediatric Care

Appendicitis holds significant importance in pediatric healthcare. It is the fifth leading reason for children's hospitalization in the U.S. and often leads to surgical intervention. However, a recent study challenges this traditional approach.

Discover the Cost-Effective and Safe Alternative to Appendectomy for Uncomplicated Appendicitis

Appendicitis: A Common Pediatric Hospitalization Reason

Appendicitis is a prevalent condition among children, accounting for a significant number of hospitalizations. The National Institutes of Health reports it as the fifth most common reason. An appendectomy is the most common procedure performed on children during hospital stays.This highlights the need for effective treatment options. Previous studies have shown the safety of treating uncomplicated cases with antibiotics alone. Now, a new study aims to determine if it is also cost-effective.

Antibiotics vs. Surgery: A Cost Analysis

Researchers analyzed data from over 1,000 young patients aged 7 to 17 admitted with acute appendicitis in the Midwest from 2015 to 2018. None of the cases were complicated. Parents chose between antibiotics for at least 24 hours or surgery.If antibiotics were not effective, laparoscopic appendectomy was performed during the same hospital stay. The study compared costs by dividing the cost by charges for hospitalization, readmissions, and unplanned emergency room visits. It captured data from about 50 children's hospitals.Patients reported data on time off from school and pain at 30 days and one year after treatment. Quality of life data was also converted to datapoints. On a scale from zero (death) to one (perfect health), it was determined that treating with antibiotics alone was both safe and cost-effective.Of 1,068 patients, 370 were treated with antibiotics, while 698 had laparoscopic appendectomy. The average cost was ,791 and a 0.884 quality-adjusted life year score per patient with surgery, compared to ,044 and 0.895 quality-adjusted life year per patient for those with antibiotics alone.

Limitations and Future Studies

The researchers noted limitations, including the short follow-up period of just one year and the fact that they only looked at cases in the Midwest. This may not be applicable to the entire country.They have further studies planned, including examining what happens with same-day discharge in both treatment populations. This will provide more insights into the long-term effects and practicality of these treatment options.In conclusion, the study presents a compelling case for considering antibiotics as a first-line treatment for uncomplicated appendicitis in children. It offers a cost-effective and safe alternative to surgery, but more research is needed to fully understand its implications.

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